This paper addresses a key issue of providing clinicians with visual inform
ation to validate the accuracy of 2-D/3-D registration for robot-assisted t
otal hip replacement (THR) surgery. Although numerous registration approach
es have been presented, the topic of registration validation has scarcely b
een addressed in the literature. In practice, clinicians rely on post-opera
tive X-rays to assess the accuracy of implant placement. Motivated by this,
we simulate a set of post-operative X-ray images by superimposing the impl
ant positioned pre-operatively onto the intra-operatively collected and cal
ibrated images of the femur, through a transformation computed by the 2-D/3
-D registration. With these images, a judgment on the registration accuracy
can be made. In addition, this paper introduces methods for superimposing
pre-operative data on intra-operative X-ray images that were not corrected
for distortion, by applying the same image distortion to the data. This pap
er also introduces a new framework for incorporating surface normals in the
objective function for registration. A comparison between marker-based and
image-based registration is conducted. The advantage of our approach is th
at the simulated post-operative X-ray images are very familiar to clinician
s and, therefore, easy for them to interpret. As an added benefit, this tec
hnique provides new means for comparing the marker-based and image-based re
gistration for robot-assisted THR surgery. This approach can be extended to
other interventions where intra-operative images are used for registration
. (C) 2000 Elsevier Science B.V. All rights reserved.