Citation
Mj. Moreno et al., Praziquantel and albendazole in the combined treatment of experimental hydatid disease, PARASIT RES, 87(3), 2001, pp. 235-238
Citations number
11
Categorie Soggetti
Microbiology
Journal title
PARASITOLOGY RESEARCH
ISSN journal
09320113
→ ACNP
Volume
87
Issue
3
Year of publication
2001
Pages
235 - 238
Database
ISI
SICI code
0932-0113(200103)87:3<235:PAAITC>2.0.ZU;2-X
Abstract
The combination of praziquantel and albendazole (PZ + ABZ) used in the pres
ent study demonstrated an efficacy of 100% when used as chemoprophylactic t
reatment because no viable hydatid cysts developed after mice had been inje
cted with protoscolices. However. when the PZ + ABZ combination was used fo
r the treatment of 4-month secondary experimental hydatidosis. no significa
nt difference was found between the control and treated mice, although seve
re damage to the cyst ultrastructure of the treated mice was observed.