Development of high numbers of blood trypomastigotes of Trypanosoma cruzi in nude rats

Authors
Schaub, GA Holscher, C Mossmann, H
Citation
Ga. Schaub et al., Development of high numbers of blood trypomastigotes of Trypanosoma cruzi in nude rats, PARASIT RES, 87(3), 2001, pp. 245-247
Citations number
21
Categorie Soggetti
Microbiology
Journal title
PARASITOLOGY RESEARCH
ISSN journal
09320113 → ACNP
Volume
87
Issue
3
Year of publication
2001
Pages
245 - 247
Database
ISI
SICI code
0932-0113(200103)87:3<245:DOHNOB>2.0.ZU;2-N
Abstract
The development and pathogenicity of a Trypanosoma cruzi strain ("Chile 5") of low virulence were studied after infection of nude rats with different doses of blood trypomastigotes (10-10(7) parasites/rat). Peak parasitemias were correlated with the infection dose, which also influenced the mean sur vival times (26-36 days post-infection). Within 26 or 27 days, a subcutaneo us injection of 10(7) blood trypomastigotes developed to about 8-20 x 10(7) parasites/ml.