Percutaneously inserted central venous lines are usually a safe and effecti
ve means of securing prolonged central venous access but can have serious c
omplications. One patient who experienced clinically important morbidity re
lated to inadvertent malpositioning of a central venous catheter is describ
ed. It was inserted via the left saphenous vein into the lumbar venous plex
us and resulted in milky cerebrospinal fluid, urine retention, and parapleg
ia, Reviewing the literature, only 11 patients with the same malposition we
re reported, three of them with percutaneously inserted central venous line
s. In these three patients and our patient the left saphenous vein was used
. Neurologic sequelae of paraplegia and urine retention were recorded in 25
% (3/12) of patients, The mortality rate approached 42% (5/12) but only two
patients were related to catheter misplacement, Although the complication
rate is extremely low and difficult to recognize, catheter malposition into
the ascending lumbar vein can lead to lethal complications. (C) 2001 by El
sevier Science inc. All rights reserved.