We hereby report on 13 cases of pericardial tamponade as the first man
ifestation of an adenocarcinoma. The primary tumor was detected in 10
cases: 7 lung, 1 stomach, 1 breast and 1 thyroid. A first cytologic ex
amination of the pericardial fluid yielded the diagnosis of adenocarci
noma in 10 cases, whereas a second cytology was needed in another two
cases. The pericardial biopsy was positive in 7 out of 7 patients. The
therapeutic procedures included pericardiocentesis in 9 patients (6 o
f whom had recurrent tamponade), a pericardial window in 4 and pericar
diotomy in 4 (without recurrences). The mean survival was 4 months.