R. Friedman et al., Psychological variables in hypertension: Relationship to casual or ambulatory blood pressure in men, PSYCHOS MED, 63(1), 2001, pp. 19-31
Objective: The evidence linking hypertension with personality or psychologi
cal characteristics, such as anger, anxiety, or depression, remains equivoc
al. This may be due in part to limitations of personality theory, confoundi
ng by awareness of hypertension, and/or inherent difficulties in measuring
blood pressure. This study was designed to investigate the association betw
een mild hypertension as defined by both ambulatory and casual (clinic) blo
od pressure measurements and various measures of personality and psychologi
cal characteristics. Methods: We examined this association in a population-
based sample of 283 men between the ages of 30 and 60 years from eight work
sites in New York City, using an ambulatory blood pressure monitor and con
trolling for age, race/ethnicity, and body mass index. Results: We found no
consistent difference between participants with mild hypertension and thos
e with normal blood pressure on any of the psychological variables assessed
, including Type A behavior pattern, state and trait anger, anger expressio
n, anxiety, symptoms of psychological distress, locus of control, or attrib
utional style. Results were not due to the use of antihypertensive medicati
on by some of the participants with hypertension nor to the dichotomization
of blood pressure into those with and without mild hypertension. This cont
rasts with previous findings from this study showing a sizable association
of ambulatory blood pressure and hypertension with job strain (a situationa
l measure), age, and body mass index. Conclusions: These null results sugge
st that situational, biological, and perhaps behavioral factors are the pri
mary determinants of mild hypertension and that the predictive significance
of psychological or dispositional factors is low or negligible in those wi
thout overt cardiovascular disease.