PURPOSE: To document the natural history of ulcerlike aortic lesions and de
termine whether any computed tomographic (CT) features predict outcome.
MATERIALS AND METHODS: CT scans from 1994 to 1998 that depicted an ulcerlik
e aortic lesion were retrospectively evaluated. Features evaluated included
lesion and aortic size and intramural hematoma. Initial CT findings were c
orrelated with clinical data and subsequent CT findings.
RESULTS: There were 56 lesions in 38 patients. Follow-up (mean, 18.4 months
) CT scans were available for 33 lesions. Stability of the lesion and adjac
ent aorta was noted in 21 lesions. Two lesions were unchanged, although ass
ociated intramural hematoma regressed over 1-2 months. Ten lesions showed m
ild to moderate increase in aortic diameter (mean follow-up, 19.8 months) e
ither with (seven lesions) or without (one lesion) increase in size of the
lesion or with incorporation of the lesion into the aortic wall contour (tw
o lesions). Of all 56 lesions, 37 were clinically stable, two were associat
ed with recurrent chest and/or back pain, eight underwent surgical resectio
n or stent placement, and two were in patients who died. Seven lesions were
in patients lost to follow-up. No initial CT feature was predictive of CT
outcome, although lack of pleural effusion correlated with clinical stabili
ty.
CONCLUSION: Most ulcerlike aortic lesions are asymptomatic and do not enlar
ge. About one-third of lesions progress, generally resulting in mild interv
al aortic enlargement.