Epidemiological typing of Candida albicans from bloodstream infections by restriction enzyme analysis

Authors
Poikonen, E Vuopio-Varkila, J Kaukoranta-Tolvanen, SS Sivonen, A Siren, E Ruutu, P
Citation
E. Poikonen et al., Epidemiological typing of Candida albicans from bloodstream infections by restriction enzyme analysis, SC J IN DIS, 33(2), 2001, pp. 140-144
Citations number
35
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
ISSN journal
00365548 → ACNP
Volume
33
Issue
2
Year of publication
2001
Pages
140 - 144
Database
ISI
SICI code
0036-5548(2001)33:2<140:ETOCAF>2.0.ZU;2-F
Abstract
Candida albicans blood culture isolates (n = 142) from 130 patients treated in 7 acute care hospitals in Southern Finland between 1986 and 1995 were t yped by restriction enzyme analysis (REA) with EcoRI and MspI. REA revealed 118 distinct Dsa types: 13 were detected in >1 patient and 105 DNA types w ere unique. Patients with identical DNA types sere not temporally! or geogr aphically clustered. Among 11 patients with more than 1 C. albicans isolate during 1 episode of fungemia the DNA type remained the same, except in 1 p atient, These results indicate that REB is a powerful tool for the epidemio logical typing of C. albicans infections.