A rare case of atraumatic splenic rupture due: to ceroid histiocytosis is d
escribed in a 56-year-old man. During hospitalization, he complained of epi
gastric pain, which was not associated with nausea or vomiting. Hematologic
indices showed steadily declining hemoglobin, and subsequent radiologic im
aging revealed massive splenomegaly. An exploratory laparotomy revealed hem
operitoneum associated with a subcapsular splenic rupture. Splenic patholog
y showed numerous ceroid-containing histiocytes, We believe this to be the
fourth reported case in the English language of atraumatic splenic rupture
due to ceroid histiocytosis.