A successful case of a hand-assisted laparoscopic splenectomy with low-pres
sure pneumoperitoneum for autoimmune thrombocytopenic purpura in a patient
at 23 weeks',gestation is reported. Preoperative splenic arterial embolizat
ion was performed on the same day as the operation using painless contour e
mbolic material and super-absorbent polymer microspheres. The abdominal wal
l retraction method first was applied to avoid the effects of pneumoperiton
eum on systemic hemodynamic alterations. However, a sufficient surgical vie
w could not be obtained, as the intra abdominal organs were elevated becaus
e of the enlarged uterus. A surgical view with 4 to 6-mm Hg pneumoperitoneu
m was available for the hand-assisted splenectomy. The postoperative course
was uneventful, and the patient vaginally delivered a healthy infant. A ha
nd-assisted laparoscopic splenectomy with low-pressure pneumoperitoneum aft
er splenic arterial embolization would be feasible for patients with autoim
mune thrombocytopenic purpura during a relatively advanced pregnancy.