The synthesis of annulated 4-quinolizinones by two sequential anionic cyclizations

Authors
Nicola, T Schwarzrock, D Keller, M Eberbach, W
Citation
T. Nicola et al., The synthesis of annulated 4-quinolizinones by two sequential anionic cyclizations, TETRAHEDRON, 57(9), 2001, pp. 1771-1777
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
9
Year of publication
2001
Pages
1771 - 1777
Database
ISI
SICI code
0040-4020(20010225)57:9<1771:TSOA4B>2.0.ZU;2-W
Abstract
Upon base treatment of N-hetaryl substituted heptynone esters of type 9 an efficient ring closure takes place affording cyclohexenone derivatives 11 w hich undergo a further anionic cyclization to provide tri- and tetracyclic quinolizinone derivatives 12 as final products. (C) 2001 Elsevier Science L td. All rights reserved.