Two new polyketide-derived macrolide lactams, identified as 73-deoxychondro
psin A (2) and chondropsin C (3), have been isolated from two different col
lections of marine sponges which belong to the genus 6 Ircinia. An Australi
an collection of Ircinia ramosa provided 73-deoxychondropsin A (2), while s
amples of Ircinia sp. collected in the Philippines yielded chondropsin C (3
). The structures of 2 and 3 were assigned by interpretation of their spect
ral data. Published by Elsevier Science Ltd.