Preparation of enantiopure 4-arylmandelic acids via a Pd/C catalysed Suzuki coupling of enantiopure 4-bromomandelic acid

Authors
Dyer, UC Shapland, PD Tiffin, PD
Citation
Uc. Dyer et al., Preparation of enantiopure 4-arylmandelic acids via a Pd/C catalysed Suzuki coupling of enantiopure 4-bromomandelic acid, TETRAHEDR L, 42(9), 2001, pp. 1765-1767
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
9
Year of publication
2001
Pages
1765 - 1767
Database
ISI
SICI code
0040-4039(20010226)42:9<1765:POE4AV>2.0.ZU;2-X
Abstract
A library of enantiomerically pure mandelic acid derivatives has been prepa red using a palladium on carbon catalysed Suzuki reaction. The chirality wa s derived from enantiomerically pure 4-bromomandelic acid which was obtaine d by resolution with alpha -methylbenzylamine. (C) 2001 Elsevier Science Lt d. All rights reserved.