The occurrence of different T cell clones in cutaneous T cell lymphoma

Authors
Drzimalla, K Simon, HU Borelli, S Simon, D
Citation
K. Drzimalla et al., The occurrence of different T cell clones in cutaneous T cell lymphoma, ALLERGOLOGI, 24(2), 2001, pp. 73-77
Citations number
15
Categorie Soggetti
Clinical Immunolgy & Infectious Disease
Journal title
ALLERGOLOGIE
ISSN journal
03445062 → ACNP
Volume
24
Issue
2
Year of publication
2001
Pages
73 - 77
Database
ISI
SICI code
0344-5062(200102)24:2<73:TOODTC>2.0.ZU;2-4
Abstract
We report on a 57-year-old patient with Sezary syndrome. The clinical diagn osis was supported by immunophenotyping of peripheral blood lymphocytes and subsequently by histological examination of skin lesions. In contrast to p reviously published cases, we observed not only one but four clones of T ce lls with atypical immunophenotype. The clonality was demonstrated by detect ion of identical V beta chains of the T cell receptor.