Predicting the risk of death from heart failure after coronary artery bypass craft surgery

Citation
Sd. Surgenor et al., Predicting the risk of death from heart failure after coronary artery bypass craft surgery, ANESTH ANAL, 92(3), 2001, pp. 596-601
Citations number
18
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ANESTHESIA AND ANALGESIA
ISSN journal
00032999 → ACNP
Volume
92
Issue
3
Year of publication
2001
Pages
596 - 601
Database
ISI
SICI code
0003-2999(200103)92:3<596:PTRODF>2.0.ZU;2-M
Abstract
Heart failure is the most common cause of death among coronary artery bypas s graft (CABG) patients. In addition, most variation in observed mortality rates for CABG surgery is explained by fatal heart failure. The purpose of this study was to develop a clinical risk assessment tool so that clinician s can rapidly and easily assess the risk of fatal heart failure while carin g for individual patients. Using prospective data for 8,641 CABG patients, we used logistic regression analysis to predict the risk of fatal heart fai lure. In multivariate analysis, female sex, prior CABG surgery, ejection fr action <40%, urgent or emergency surgery, advanced age (70-79 yr and >80 yr ), peripheral vascular disease, diabetes, dialysis-dependent renal failure and three-vessel coronary disease were significant predictors of fatal post operative heart failure. A clinical risk assessment tool was developed from this logistic regression model, which had good discriminating characterist ics (receiver operating characteristic clinical source = 0.75, 95% confiden ce interval: 0.71, 0.78).