Heart failure is the most common cause of death among coronary artery bypas
s graft (CABG) patients. In addition, most variation in observed mortality
rates for CABG surgery is explained by fatal heart failure. The purpose of
this study was to develop a clinical risk assessment tool so that clinician
s can rapidly and easily assess the risk of fatal heart failure while carin
g for individual patients. Using prospective data for 8,641 CABG patients,
we used logistic regression analysis to predict the risk of fatal heart fai
lure. In multivariate analysis, female sex, prior CABG surgery, ejection fr
action <40%, urgent or emergency surgery, advanced age (70-79 yr and >80 yr
), peripheral vascular disease, diabetes, dialysis-dependent renal failure
and three-vessel coronary disease were significant predictors of fatal post
operative heart failure. A clinical risk assessment tool was developed from
this logistic regression model, which had good discriminating characterist
ics (receiver operating characteristic clinical source = 0.75, 95% confiden
ce interval: 0.71, 0.78).