Rhabdomyosarcoma is a soft tissue tumor of striated muscle origin. It is ob
served mainly in children and adolescents. Rhabdomyosarcoma predominantly o
ccurs in three regions: head and neck, genito-urinary tract and retroperito
neum, and upper and lower extremities. We report a case of primary alveolar
rhabdomyosarcoma of the mesentery occurring in a 68-year-old man. Rhabdomy
osarcomas can be diagnosed on microscopic findings and immunohistochemical
features. Cyto-genetic findings con be helpful in the diagnosis.