Interaction of diphenyltin(IV) dichloride with some selected bioligands

The interaction of diphenyltin(IV) with selected bioligands having a variet y of model functional groups were investigated using the potentiometric tec hnique. The hydrolysis constants of diphenyltin(IV) cation and the step-wis e formation constants of the complexes formed in solution were calculated u sing the non linear least-squares program MINIQUAD-75. The participation of different ligand functional groups in binding to organotin is discussed, T he concentration distribution of the various complex species,vas evaluated as a function of pH.