We present a new and unique software capability for finding statistical opt
imal designs of deterministic experiments on continuous cuboidal regions. T
he objective function for the design optimization is the minimization of th
e expected integrated mean squared error of prediction of the metamodel tha
t will be found, subsequent to the running of the computer simulations, usi
ng the best linear unbiased predictor (BLUP). The assumed response-model fu
nction includes an unknown, stochastic term, Z. We prove that this criterio
n, which we name I-z-optimality, is equivalent to I-z-optimality for non-de
terministic experiments, in the limit of zero correlations among the Z's fo
r different inputs. An example is presented of metamodel generation for a m
icromachined-silicon flow sensor. The I-z-optimal set of inputs is found, f
inite-element (FE) simulations run, and the metamodel generated using a BLU
P fit. The method is compared to other approaches. I-z-optimality, coupled
with BLUP fitting, provides a highly efficient means of non-parametric meta
model generation. I-z-optimal design searching and BLUP fitting are new opt
ions of the I-OPT(TM)d program that is available on the World-Wide Web at U
RL http://www-personal.engin.umich.edu/similar to crary/iopt.