Southern hybridization with probes designed for detection of WD-repeats cod
ing sequences gave positive results in 21 streptomycete strains indicating
that WD-repeats encoding genes are massively spread among streptomycetes. O
ne of them, the wdlA gene of Streptomyces lincolnensis, codes for a 971 ami
no acid protein with seven WD-repeats in its C-terminus, two transmembrane
domains and an ATP/GTP binding site upstream of the WD-repeat region.