Amplification of AML1 in childhood acute lymphoblastic leukemias

Authors
Dal Cin, P Atkins, L Ford, C Ariyanayagam, S Armstrong, SA George, R Cleary, A Morton, CC
Citation
P. Dal Cin et al., Amplification of AML1 in childhood acute lymphoblastic leukemias, GENE CHROM, 30(4), 2001, pp. 407-409
Citations number
17
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
GENES CHROMOSOMES & CANCER
ISSN journal
10452257 → ACNP
Volume
30
Issue
4
Year of publication
2001
Pages
407 - 409
Database
ISI
SICI code
1045-2257(200104)30:4<407:AOAICA>2.0.ZU;2-8
Abstract
Amplification of AML1 has been confirmed by fluorescence in situ hybridizat ion analysis in two cases of childhood acute lymphoblastic leukemia. It rem ains to be elucidated whether this amplification results in up-regulation o f the normal AML I gene product or a potentially mutant AML1 transcript. (C ) 2001 Wiley-Liss, Inc.