Long-term phase of schizophrenia: impact of atypical agents

Typical antipsychotic agents are poorly suited to the long-term treatment o f schizophrenia, particularly since the introduction of atypical compounds has increased the expectations of both physicians and patients. Well-being and quality of life-now important considerations-have shown significant imp rovements in patients treated with atypical agents such as amisulpride rath er than typical agents such as haloperidol. This is associated with allevia tion of negative symptoms and cognitive deficits, benefits which are not se en with traditional agents and which increase the likelihood of successful rehabilitation. Int clin Psychopharmacol 2000, 15 (suppl 4):S11-S14 (C) 200 0 Lippincott Williams & Wilkins.