Diagnosis of severe combined immunodeficiency

Authors
Gennery, AR Cant, AJ
Citation
Ar. Gennery et Aj. Cant, Diagnosis of severe combined immunodeficiency, J CLIN PATH, 54(3), 2001, pp. 191-195
Citations number
35
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF CLINICAL PATHOLOGY
ISSN journal
00219746 → ACNP
Volume
54
Issue
3
Year of publication
2001
Pages
191 - 195
Database
ISI
SICI code
0021-9746(200103)54:3<191:DOSCI>2.0.ZU;2-Y
Abstract
Early diagnosis of severe combined immunodeficiency (SCID) is important to enable prompt referral to a supraregional centre for bone marrow transplant ation before the occurrence of end organ damage secondary to infective comp lications. This review outlines clinical, microbiological, and immunopathol ogical clues that aid the diagnosis of SCID and emphasises the multidiscipl inary approach needed to diagnose and treat these infants.