Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi

Authors
Utkina, NK Denisenko, VA Scholokova, OV Virovaya, MV Gerasimenko, AV Popov, DY Krasokhin, VB Popov, AM
Citation
Nk. Utkina et al., Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi, J NAT PROD, 64(2), 2001, pp. 151-153
Citations number
16
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
2
Year of publication
2001
Pages
151 - 153
Database
ISI
SICI code
0163-3864(200102)64:2<151:SAABTN>2.0.ZU;2-G
Abstract
Two new cytotoxic tetrabromodibenzo-p-dioxins, spongiadioxins A(1)and B (2) , were isolated from an Australian marine sponge Dysidea dendyi. The struct ures of these compounds were established by 1D and 2D NMR spectroscopy, X-r ay analysis of the methyl ether of spongiadioxin A (3), and synthesis of th e methyl ether of spongiadioxin B (4) from diphenyl ether (9) isolated from Dysidea herbacea.