Nk. Utkina et al., Spongiadioxins A and B, two new polybrominated dibenzo-p-dioxins from an Australian marine sponge Dysidea dendyi, J NAT PROD, 64(2), 2001, pp. 151-153
Two new cytotoxic tetrabromodibenzo-p-dioxins, spongiadioxins A(1)and B (2)
, were isolated from an Australian marine sponge Dysidea dendyi. The struct
ures of these compounds were established by 1D and 2D NMR spectroscopy, X-r
ay analysis of the methyl ether of spongiadioxin A (3), and synthesis of th
e methyl ether of spongiadioxin B (4) from diphenyl ether (9) isolated from
Dysidea herbacea.