HTLV-I-associated granulomatous T-cell lymphoma in a child

Citation
Jm. Lewis et al., HTLV-I-associated granulomatous T-cell lymphoma in a child, J AM ACAD D, 44(3), 2001, pp. 525-529
Citations number
33
Categorie Soggetti
Dermatology,"da verificare
Journal title
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
ISSN journal
01909622 → ACNP
Volume
44
Issue
3
Year of publication
2001
Pages
525 - 529
Database
ISI
SICI code
0190-9622(200103)44:3<525:HGTLIA>2.0.ZU;2-H
Abstract
Adult T-cell leukemia/lymphoma (ATLL) is a T-cell malignancy closely associ ated with human T-cell lymphotropic virus-1 (HTLV-I). Because of its long l atency period, ATLL occurs almost exclusively in adults. We report a case o f a 13-year-old boy with an 8-year history of skin eruptions. After complet e evaluation, a diagnosis of HTLV-I-associated lymphoma/leukemia was made. The T-cell lymphoma exhibited a granulomatous histomorphology. There have b een very few reports of ATLL presenting in childhood and none, to our knowl edge, demonstrating granulomatous histology. We conclude that ATLL may rare ly present as a chronic granulomatous eruption in a child.