A density-matrix theoretical model to calculate spectral line profiles of g
eneral multielectron ions in plasmas is described. The line-profile calcula
tion involves electron collisional and radiative relaxation of ionic states
, the emitter's motion (Doppler effect) and its interaction with a quasi-st
atic ion microfield. Using the LineDM computer package implementing this mo
del, line-profile calculations of the K- and L-shell transitions in Al XII,
Ar XVII, Ar XVI, Cu XX, and Xe XLV ions have been performed in the context
of plasma diagnostic issues of recent laboratory experiments. Comparisons
of the calculated line profiles with experimental and other theoretical dat
a show the applicability of the model and package for the detailed computat
ional analysis of line radiation spectra from multielectron emitters in hot
dense plasmas.