Antibiotic resistance of Staphylococcus aureus isolated from community andnosocomial infections in Casablanca.

Objective - The resistance patterns to 11 antibiotics of 156 community acqu ired and 189 nosocomial Staphylococcus aureus isolated during two periods a t the IbnRochd University Hospital of Casablanca were determined. Material and methods - Defection of methicillin resistance was performed us ing the agar screen technique with 6 mg/L of oxacillin and resistance to ot her antibiotics was studied using the NCCLS disk diffusion method. Results - Methicillin resistance levels were 1.9% and 45% for community and nosocomial isolates respectively. MRSA isolates were multiresistant (genta micin 84.7%, cotrimoxazole 51.2%, erythromycin 44.7%, fusidic acid 45.9%, c iprofloxacin 83.5%). MRSA isolates were mostly isolated from the surgery de partment (46.2%) during the first period and from the ICU (61%) during the second period. MRSA were isolated mainly from blood (34.1%), pus (34.6%), a nd respiratory tract (27.1%). (C) 2001 Editions scientifiques et medicales Elsevier SAS.