Guard cells are located in the epidermis of plant leaves, and in pairs surr
ound stomatal pores. These control both the influx of CO2 as a raw material
for photosynthesis and water loss from plants through transpiration to the
atmosphere. Guard cells have become a highly developed system for dissecti
ng early signal transduction mechanisms in plants. In response to drought,
plants synthesize the hormone abscisic acid, which triggers closing of stom
ata, thus reducing water loss. Recently, central regulators of guard cell a
bscisic acid signalling have been discovered. The molecular understanding o
f the guard cell signal transduction network opens possibilities for engine
ering stomatal responses to control CO2 intake and plant water loss.