NEUROSURGICAL TREATMENT FOR psychiatric disorders has a long and controvers
ial history. From the Stone Age use of trephining to release the demons of
the spirit to the millimeter accuracy of stereotactic instruments currently
used in the operating room, psychosurgery has enjoyed enthusiastic support
as well as experiencing scorn. Today, psychosurgery is a minimally invasiv
e and highly selective treatment that is performed for only a few patients
with severe, treatment-refractory, affective, anxiety, or obsessive-compuls
ive disorders. Recent advances in technology and functional neuroanatomic t
echniques, as well as economic pressures to decrease the costs of caring fo
r chronically ill patients, may provide an opportunity for psychosurgery to
become a more attractive option for the treatment of psychiatric diseases.
In this historical overview, the rise and fall of psychosurgery are descri
bed. A better understanding of the colorful history of this interesting top
ic should enable modern neurosurgeons and other health care professionals t
o meet the social, ethical, and technical challenges that are sore to lie a
head.