OBJECTIVE AND IMPORTANCE: Neoplasms of peripheral nerves can be obscured, e
specially during the early phase. The author reports a patient with a poste
rior tibial nerve neurilemoma (schwannoma). For a decade, the tumor was mis
diagnosed as nonspecific S1 radiculopathy and psychogenic chronic pain synd
rome. The patient's presentation and initial management are unique.
CLINICAL PRESENTATION: A 40-year-old woman reported severe left foot and ca
lf pain, numbness, and weakness. The symptoms were evident during three pre
gnancies, and they gradually progressed. The neuropathic pain was protracte
d, despite implantation of a dorsal column stimulator and administration of
a wide variety of medications and therapies. The symptoms were unresponsiv
e to both inpatient and outpatient treatments, which resulted in a misdiagn
osis of psychogenic pain for more than a decade. Diagnostic scans obtained
by computed tomography, ultrasonography, and nuclear scintigraphy confirmed
a popliteal fossa mass.
INTERVENTION: A high, large posterior tibial nerve neurilemoma was found in
traoperatively, positioned just below the sciatic nerve bifurcation with ex
tensive degenerative features and hemorrhages. Surgical resection provided
immediate recovery.
CONCLUSION: Peripheral nerve tumors are rarely acknowledged clinical entiti
es. Chronic unexplained foot and calf pain and a positive Tinel's sign shou
ld raise suspicion of posterior tibial nerve neurilemoma. Even in patients
who have had such tumors for a decade, surgical resection remains the treat
ment of choice.