GeneSplicer: a new computational method for splice site prediction

Citation
M. Pertea et al., GeneSplicer: a new computational method for splice site prediction, NUCL ACID R, 29(5), 2001, pp. 1185-1190
Citations number
15
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEIC ACIDS RESEARCH
ISSN journal
03051048 → ACNP
Volume
29
Issue
5
Year of publication
2001
Pages
1185 - 1190
Database
ISI
SICI code
0305-1048(20010301)29:5<1185:GANCMF>2.0.ZU;2-P
Abstract
GeneSplicer is a new, flexible system for detecting splice sites in the gen omic DNA of various eukaryotes, The system has been tested successfully usi ng DNA from two reference organisms: the model plant Arabidopsis thaliana a nd human. It was compared to six programs representing the leading splice s ite detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSp lice, GENIO and SpliceView. In each case GeneSplicer performed comparably t o the best alternative, in terms of both accuracy and computational efficie ncy.