GeneSplicer is a new, flexible system for detecting splice sites in the gen
omic DNA of various eukaryotes, The system has been tested successfully usi
ng DNA from two reference organisms: the model plant Arabidopsis thaliana a
nd human. It was compared to six programs representing the leading splice s
ite detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSp
lice, GENIO and SpliceView. In each case GeneSplicer performed comparably t
o the best alternative, in terms of both accuracy and computational efficie
ncy.