A prospective, controlled, observer-masked study was conducted to investiga
te the suitability of contact lenses for patients with diabetes mellitus. F
orty diabetic patients and 40 non-diabetic control subjects were fitted wit
h soft hydrogel contact lenses to be worn on a daily wear basis for 12 mont
hs. The ocular response was assessed using slit lamp biomicroscopy, ultraso
nic pachometry, corneal aesthesiometry and visual acuity measures. Compared
to non-diabetic subjects, diabetic patients displayed significantly reduce
d corneal transparency, variable vision and reduced comfort with the contac
t lenses (p < 0.05). There were no significant differences between the two
groups with respect to ocular hyperaemia, corneal staining, corneal thickne
ss, corneal sensitivity or high contrast visual acuity. Contrary to previou
s reports, the response of the diabetic eye to contact lenses-as observed c
linically-does not differ appreciably from that of the non-diabetic eye. Th
ese results suggest that current generation daily wear soft contact lenses
can be a viable mode of vision correction for diabetic patients. (C) 2001 T
he College of Optometrists. Published by Elsevier Science Ltd. All rights r
eserved.