Hairpin formation and elongation of biomolecules

Citation
A. Montanari et M. Mezard, Hairpin formation and elongation of biomolecules, PHYS REV L, 86(10), 2001, pp. 2178-2181
Citations number
22
Categorie Soggetti
Physics
Journal title
PHYSICAL REVIEW LETTERS
ISSN journal
00319007 → ACNP
Volume
86
Issue
10
Year of publication
2001
Pages
2178 - 2181
Database
ISI
SICI code
0031-9007(20010305)86:10<2178:HFAEOB>2.0.ZU;2-F
Abstract
We introduce a model of thermalized conformations in space of RNA - or sing le stranded DNA - molecules, which includes the possibility of hairpin form ation. This model contains the usual secondary structure information, but e xtends it to the study of one element of the ternary structure. namely the end-to-end distance. The computed force-elongation characteristics are in g ood agreement with sonic recent measurements on single stranded DNA molecul es.