A correlation between renal morphology and renal circulation in pediatric nephrotic syndrome

A morphometric analysis of the renal biopsy specimens and intrarenal hemody namic study were performed in 37 pediatric patients with idiopathic nephrot ic syndrome. The study indicated an inverse correlation between intrarenal hemodynamics (renal plasma flow and peritubular capillary flow) and a relat ive area of renal cortical interstitium. In respect to the glomerular study , the incidence of glomerulosclerosis increased as the renal perfusion decr eased, however, the correlation did not reach a statistical significance.