Combinatorial analysis - How much is it worth?

Authors
Citation
Jv. Busch, Combinatorial analysis - How much is it worth?, RES TECH M, 44(2), 2001, pp. 38-45
Citations number
4
Categorie Soggetti
Management,"Engineering Management /General
Journal title
RESEARCH-TECHNOLOGY MANAGEMENT
ISSN journal
08956308 → ACNP
Volume
44
Issue
2
Year of publication
2001
Pages
38 - 45
Database
ISI
SICI code
0895-6308(200103/04)44:2<38:CA-HMI>2.0.ZU;2-L
Abstract
Combinatorial research methods are fundamental to the pharmaceutical and bi otechnology industries. Instead of making small numbers of compounds and th en testing them for desired attributes, researchers are producing and scree ning thousands of compounds at a time in automated research facilities. The result: more promising compounds, more commercial starts, and more financi al success. These same methods are beginning to be applied to other industr ies such as materials or chemicals. From a financial perspective, the poten tial benefit of combinatorial research is derived from two factors. increas ing speed to market and enabling premium pricing. By interviewing senior ma rket development personnel and modeling their responses. a quantitative fin ancial assessment was made of the value of combinatorial research methods.