Diagnosing renovascular hypertension is complex. Definitive diagnosis can o
nly be made in retrospect, when a hypertensive patient with renal artery st
enosis improves following correction of the stenotic arterial lesion. Scree
ning for renovascular hypertension in all hypertensive patients is impracti
cal because of the low prevalence of the disease. However, the diagnosis is
important because treatment can lead to potential cure. A select group of
patients with clinical signs and symptoms suggesting renovascular hypertens
ion need to be investigated further for the cause of their hypertension. A
number of clinical tests help in screening patients that require further im
aging tests. The tests designed for evaluating renovascular hypertension as
sess the functional and anatomic abnormalities. This article reviews variou
s clinical and imaging techniques available for evaluating these patients.
A description of each technique is followed by a discussion of its advantag
es and disadvantages. The authors also propose an algorithm for work-up of
patients with a high probability of renovascular hypertension.