Quaternary ammonium salt-assisted organic reactions in water: Alkylation of phenols

Citation
Jj. Vanden Eynde et I. Mailleux, Quaternary ammonium salt-assisted organic reactions in water: Alkylation of phenols, SYN COMMUN, 31(1), 2001, pp. 1-7
Citations number
44
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
31
Issue
1
Year of publication
2001
Pages
1 - 7
Database
ISI
SICI code
0039-7911(2001)31:1<1:QASORI>2.0.ZU;2-6
Abstract
A series of quaternary ammonium salts has been tested as phase transfer age nts to promote reactions between phenols and alkyl halides in an aqueous so lution of sodium hydroxide in the absence of organic solvent. Methyltriocty lammonium chloride emerges as the most effective catalyst.