Results of long-term treatment with a novel mucolytic drug pulmozim in mucoviscidosis patients

Citation
Ni. Kapranov et al., Results of long-term treatment with a novel mucolytic drug pulmozim in mucoviscidosis patients, TERAPEVT AR, 73(1), 2001, pp. 55-58
Citations number
4
Categorie Soggetti
General & Internal Medicine
Journal title
TERAPEVTICHESKII ARKHIV
ISSN journal
00403660 → ACNP
Volume
73
Issue
1
Year of publication
2001
Pages
55 - 58
Database
ISI
SICI code
0040-3660(2001)73:1<55:ROLTWA>2.0.ZU;2-5
Abstract
Aim. To study clinical effectiveness and safety of a new mucolytic drug pul mozim (Swetzeland) adjuvant to basic therapy in mucoviscidosis patients of different age in Russia. Material and methods. 15 patients with mucoviscidosis aged 5-36 years, func tional lung capacity and FEV-1 at least 40% received pulmozim for 30 days. The drug was given in a single daily dose 2.5 mg in inhalations. The study included three stages: initial 14 days - discontinuation of all mucolytic d rugs, 30-day course of pulmozim, 14-day follow-up without pulmozin and othe r mucolytics. Results. Pulmozim in the above regimen was effective in patients with mixed and moderate mucoviscidosis. The drug facilitates respiration, improves sp utum rheology, normalizes general condition of the patient, is simple for u se, has good organoleptic properties. Conclusion. Pulmozim is an effective mucolytic drug in combined treatment o f mucoviscidosis.