Usefulness of handgrip to improve ibutilide efficacy in organizing atrial electrical activity during atrial fibrillation

Authors
Pitzalis, MV Grimaldi, M Anaclerio, M Iacoviello, M Luzzi, G Forleo, C Rizzon, P
Citation
Mv. Pitzalis et al., Usefulness of handgrip to improve ibutilide efficacy in organizing atrial electrical activity during atrial fibrillation, AM J CARD, 87(6), 2001, pp. 798
Citations number
10
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
87
Issue
6
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010315)87:6<798:UOHTII>2.0.ZU;2-U
Abstract
We analyzed the effect of handgrip on atrial electrical activity during atr ial fibrillation (AF) by recording right and left atrial activity in 15 pat ients with persistent AF under baseline conditions and after saline and ibu tilide infusions. The handgrip test for 15 seconds, which was always associ ated with a significant increase in mean atrial cycle length, was recorded in both atria (right atrium: saline vs saline + handgrip 141 +/- 29 vs 171 +/- 24 ms, p <0.001; ibutilide vs and grip: 197 +/- 43 vs 221 +/- 39 ms, p <0.005). Handgrip favorably modifies atrial electrophysiologic properties d uring AF.