Plasma levels of vascular endothelial growth factor and its soluble receptor (sFlt-1) in essential hypertension

Authors
Belgore, FM Blann, AD Li-Saw-Hee, FL Beevers, DG Lip, GYH
Citation
Fm. Belgore et al., Plasma levels of vascular endothelial growth factor and its soluble receptor (sFlt-1) in essential hypertension, AM J CARD, 87(6), 2001, pp. 805
Citations number
3
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
87
Issue
6
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010315)87:6<805:PLOVEG>2.0.ZU;2-X
Abstract
In this study of 27 untreated patients with uncomplicated essential hyperte nsion, we report on elevated plasma levels of vascular endothelial growth f actor and its soluble receptor FIt-1 compared with healthy controls; these increased levels are reduced by the treatment of hypertension. This raises the possibility that abnormal angiogenesis may contribute to the pathogenes is of complications related to hypertension and merits exploration in large r studies.