Cj. Moody et al., ADDITION OF ORGANOLITHIUMS TO THE (R)-O-(1-PHENYLBUTYL)HYDROXYLAMINE (ROPHY) OXIME OF CINNAMALDEHYDE - ASYMMETRIC-SYNTHESIS OF ALPHA-AMINO-ACIDS, Synlett, (6), 1997, pp. 659-660
A new asymmetric synthesis of alpha-aminoacids is described in which t
he key step is the diastereoselective addition of organolithium reagen
ts to (R)-O-(1-phenylbutyl) cinnamaldoxime.