Spinal cord involvement in primary angiitis of the central nervous system:A report of two cases

We report two patients with suspected primary angiitis of the CNS who under went serial contrast-enhanced MR imaging of the spinal cord. MR abnormaliti es were multiple and enhancing, and located within the cervical and thoraci c cord. Brain MR findings and brain biopsy specimens were positive for prim ary angiitis of the CNS, On follow-up MR studies, obtained after steroid an d immunosuppressive therapy, a significant decrease in the number and size of the enhancing and nonenhancing abnormalities was observed, along with cl inical improvement. Numerous small and enhancing abnormalities with a prima rily posterior location, seen at the onset of the disease and resolved on f ollow-up studies, may be considered suggestive of a diagnosis of primary an giitis of the CNS.