ENANTIOSELECTIVE SYNTHESIS OF GAMMA-HYDROXYNORVALINE

Authors
JACOB M ROUMESTANT ML VIALLEFONT P MARTINEZ J
Citation
M. Jacob et al., ENANTIOSELECTIVE SYNTHESIS OF GAMMA-HYDROXYNORVALINE, Synlett, (6), 1997, pp. 691-692
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
6
Year of publication
1997
Pages
691 - 692
Database
ISI
SICI code
0936-5214(1997):6<691:ESOG>2.0.ZU;2-L
Abstract
A new synthesis of enantiomerically pure gamma-hydroxynorvaline is des cribed. The key step involves diastereoselective alkylation of the chi ral Schiff base 1 with primary iodo derivatives 2 easily prepared from propylene oxide.