Defective recognition of one's own actions in patients with schizophrenia

Objective: The possibility that delusions of influence could be related to abnormal recognition of one's own actions was investigated in persons with schizophrenia. Method: Schizophrenic patients with (N=6) and without (N=18) delusions of i nfluence were compared with normal subjects (N=29) on an action recognition task. The image of a virtual right hand hording a joystick was presented t o the subjects through a mirror so that the image was superimposed on their real hand holding a real joystick. Subjects executed discrete movements in different directions. Angular biases and temporal delays were randomly int roduced in some trials, such that the movement of the virtual hand departed from the movement executed by the subjects. After each trial, subjects wer e asked whether the movement they saw was their own. Results: Compared with normal subjects, both patient groups made significan tly more recognition errors in trials with temporal delays. In trials with angular biases, the error rate of patients with delusions of influence sign ificantly differed from that of comparison subjects and from that of patien ts without delusions of influence. Conclusions: The findings support the hypothesis that delusions of influenc e are associated with a quantifiable difficulty in correct self-attribution of actions. This difficulty may be related to a specific impairment of a n eural action attribution system.