Synovial cytokine mRNA expression during arthritis triggered by CpG motifsof bacterial DNA

Authors
Deng, GM Tarkowski, A
Citation
Gm. Deng et A. Tarkowski, Synovial cytokine mRNA expression during arthritis triggered by CpG motifsof bacterial DNA, ARTHRITIS R, 3(1), 2001, pp. 48-53
Citations number
43
Categorie Soggetti
Rheumatology
Journal title
ARTHRITIS RESEARCH
ISSN journal
14659913 → ACNP
Volume
3
Issue
1
Year of publication
2001
Pages
48 - 53
Database
ISI
SICI code
1465-9913(2001)3:1<48:SCMEDA>2.0.ZU;2-#
Abstract
Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG O DN). IL-12 is in this respect an important immunomodulator during the devel opment of joint inflammation.