Objective: To estimate the number of coronary events that could be prevente
d in Australia each year by the use of preventive and therapeutic strategie
s targeted to subgroups of the population based on their levels of risk and
need.
Methods: Estimates of risk reduction from the published literature, prevale
nce estimates of elevated risk factor levels from the 1995 National Health
Survey and treatment levels from the Australian collaborating centres in th
e World Health Organization's MONICA Project were used to calculate numbers
of coronary events preventable among men and women aged 35-79 years in Aus
tralia.
Results: Approximately 14,000 coronary events could be avoided each year if
the mean level of cholesterol in the population was reduced by 0.5 mmol/L,
smoking prevalence was halved and prevalence of physical inactivity was re
duced to 25%. This represents a reduction in coronary events of about 40%.
Even with less optimistic targets, a reduction of 20% could be attained, wh
ile the achievement of some internationally recommended targets could lead
to almost 50% reduction. In the short term, aggressive medical treatment of
people with elevated levels of risk factors and established coronary disea
se offers the greatest opportunity for reducing coronary events.
Conclusion: A comprehensive approach to reduce levels of behavioural and bi
ological risk factors and improve the use of effective treatment could lead
to a large reduction in coronary event rates. In the long term, primary pr
evention - especially to reduce smoking, lower cholesterol levels and incre
ase exercise - has the potential to reduce the population levels of risk an
d hence contain the national cost of coronary disease.