Dynamic model of amperometric biosensors. Characterisation of glucose biosensor output

An integrated model for the characterisation of the output signal course of oxidase-bound amperometric biosensors is presented and evaluated in the ca se of glucose biosensors. This model integrates two earlier proposed models , the model of oxygen transducer-based biosensors. allowing the prediction of steady state parameters from the transient response and the dynamic sign al lag model, characterising the electrochemical diffusion-limited sensors. The integrated model allows the characterisation of the whole biosensor si gnal output. originating from the output curve itself with errors less than 3% and no need to determine the system's geometrical. diffusion and partit ion parameters. (C) 2001 Elsevier Science B.V. All rights reserved.