Deprivation and late presentation of glaucoma: case-control study

Objective To identify socioeconomic risk factors for first presentation adv anced glaucomatous visual field loss. Design Hospital based case-control study with prospective identification of patients. Setting Three hospital eye departments. Participants Consecutive patients newly diagnosed with glaucoma (n = 220). Cases (late presenters) were those presenting with advanced glaucoma (n = 1 10), controls were those with early glaucoma (n = 110). Results Median underprivileged area scores were higher among late presenter s (29.5; interquartile range 9.0-42.2) than in the control group (21.3; 6.1 -37.4) (P = 0.035). Late presenters were more likely to be of lower occupat ional class (odds ratio adjusted for age and referral centre 20.1 (95% conf idence interval 2.6 to 155) for group III compared with group I-Il and 86.0 (11.0 to 673 for group TV-V compared with group I-IT), to have no access t o a car (2.2; 1.2 to 4.0), to have left full time education at age 14 or le ss (7.5; 2.3 to 24.7), and to be tenants rather than owner occupiers (local authority tenants 3.2; 1.7 to 5.8, private tenants 2.1; 0.7 to 5.8). Effec ts of deprivation were paltry accounted for by family history of glaucoma, time since last visit to an optometrist and lack of an initial diagnosis of glaucoma by an optometrist Conclusions Area and individual level deprivation were both associated with late presentation of glaucoma. Existing evidence shows that late presentat ion is an important risk factor for subsequent blindness. Deprived groups t hus seem to be at greater risk of going blind from glaucoma. Material depri vation may be associated with more aggressive disease as well as later pres entation.