Structural revision of isovalertatins M03, M13, and M23 isolated from the culture of Streptomyces luteogriseus

Three aminooligosaccharides, isovalertatins M03 (1), M13 (2), and M23 (3) w ere isolated and purified from the culture filtrate of Streptomyces luteogr iseus. Their physicochemical properties, liquid chromatographic behavior, a nd spectroscopic data were in full accordance with the reported compounds [ Xu, Q.; Wang, Q.; Lu, D. CN Patent 1100756, 1995; Chem. Abstr. 1995, 123, 1 10278n], but their structures were reinvestigated and revised by spectrosco pic methods, including ESI multistage mass spectrometry and 2-dimensional N MR techniques. (C) 2001 Elsevier Science Ltd. All rights reserved.