In vivo tracking of tumor-specific T cells

Authors
Yee, C Riddell, SR Greenberg, PD
Citation
C. Yee et al., In vivo tracking of tumor-specific T cells, CURR OP IM, 13(2), 2001, pp. 141-146
Citations number
48
Categorie Soggetti
Immunology
Journal title
CURRENT OPINION IN IMMUNOLOGY
ISSN journal
09527915 → ACNP
Volume
13
Issue
2
Year of publication
2001
Pages
141 - 146
Database
ISI
SICI code
0952-7915(200104)13:2<141:IVTOTT>2.0.ZU;2-T
Abstract
Novel immunologic assays now enable visualization of the antigen-specific r esponse to an extent not previously possible. Assessment of not only the nu meric frequency but also the functional properties of individual tumor-spec ific T cells in the endogenous and manipulated immune response has provided insights that will facilitate the development of immunotherapeutic strateg ies.