The influence of thrombus components in mediating bacterial adhesion to biomaterials

Authors
Lamba, NMK Baumgartner, JN Cooper, SL
Citation
Nmk. Lamba et al., The influence of thrombus components in mediating bacterial adhesion to biomaterials, J BIOM SC P, 11(11), 2000, pp. 1227-1237
Citations number
62
Categorie Soggetti
Multidisciplinary
Journal title
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
ISSN journal
09205063 → ACNP
Volume
11
Issue
11
Year of publication
2000
Pages
1227 - 1237
Database
ISI
SICI code
0920-5063(2000)11:11<1227:TIOTCI>2.0.ZU;2-6
Abstract
Thrombosis and infection represent the two largest limiting factors determi ning the long term success of implanted biomaterials. Infections associated with biomaterials are difficult to treat, and appear to evade the host def ense systems. Mechanisms relating infection to thrombosis are described. In vestigations into the role of receptors in mediating adhesion to thrombi ar e also discussed, in addition to strategies to reduce bacterial adhesion to biomaterial surfaces.